 Health Guide Drug Guide Simian crease A simian crease is a single palmar crease as compared to two creases in a normal palm. Simian crease occurs in about 1 out of 30 normal people, but is also frequently associated with other conditions such as Down syndrome, Aarskog syndrome or fetal alcohol syndrome. 
Review Date:
2/5/2008 Reviewed By: Chad Haldeman-Englert, MD, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA. Review provided by VeriMed Healthcare Network. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997-
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