BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down.
A test can be done to measure the amount of urea nitrogen in the blood.
Alternative Names
Blood urea nitrogen
How the Test is Performed
Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.
Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.
Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.
How to Prepare for the Test
Many drugs affect BUN levels. Before having this test, make sure the health care provider knows which medications you are taking.
Drugs that can increase BUN measurements include:
Allopurinol
Aminoglycosides
Amphotericin B
Aspirin (high doses)
Bacitracin
Carbamazepine
Cephalosporins
Chloral hydrate
Cisplatin
Colistin
Furosemide
Gentamicin
Guanethidine
Indomethacin
Methicillin
Methotrexate
Methyldopa
Neomycin
Penicillamine
Polymyxin B
Probenecid
Propranolol
Rifampin
Spironolactone
Tetracyclines
Thiazide diuretics
Triamterene
Vancomycin
Drugs that can decrease BUN measurements include:
Chloramphenicol
Streptomycin
How the Test Will Feel
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the Test is Performed
The BUN test is often done to check kidney function.
Normal Results
7 - 20 mg/dL. Note that normal values may vary among different laboratories.
Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks are slight but may include:
Excessive bleeding
Fainting or feeling light-headed
Hematoma (blood accumulating under the skin)
Infection (a slight risk any time the skin is broken)
Considerations
For people with liver disease, the BUN level may be low even if the kidneys are normal.
Review Date:
5/13/2009
Reviewed By:
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.