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Buccal smear

Definition

A buccal smear (pronounced "buckle") is the painless removal of a sample of cells from the lining of the mouth (inside of the cheek) for study.

Alternative Names

Sex chromatin test

How the Test is Performed

The health care provider will gently scrape the inside of the cheek with a small spatula to collect cells for testing.

How to Prepare for the Test

Rinse, wash and swab the mouth as instructed for the particular test ordered.

How the Test Will Feel

You will feel a scraping sensation as cells are removed from the cheek.

Why the Test is Performed

This procedure is used to obtain cells for DNA and chromosome testing for several genetic disorders. It can be used for rapid analysis in the newborn to determine gender or chromosomal abnormalities.

Risks

There are no risks associated with the buccal smear.


Review Date: 12/11/2006
Reviewed By: Brian Kirmse, MD, Mount Sinai School of Medicine, Department of Human Genetics, New York, NY. Review provided by VeriMed Healthcare Network.
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