Urethritis is inflammation of the urethra from any cause.
Causes
Urethritis may be caused by bacteria or a virus. The same bacteria that cause urinary tract infections (E. coli) and some sexually transmitted diseases (chlamydia, gonorrhea) can lead to urethritis. Viral causes of urethritis include herpes simplex virus and cytomegalovirus.
Other causes include:
Sensitivity to the chemicals used in spermicides or contraceptive jellies, creams, or foams
Injury
Risks for urethritis include:
High-risk sexual behavior (such as anal sex without a condom)
The health care provider will perform a physical examination. In men, the exam will include the abdomen, bladder area, penis, and scrotum. The physical exam may show:
Antibiotic therapy should target the bacteria causing the infection. In some cases, antibiotics may need to be given through a vein (by IV). You may take pain relievers (including pyridium, which works on the urinary tract) along with antibiotics.
People with urethritis who are being treated should avoid sex or use condoms during sex. If an infection is the cause of the inflammation, your sexual partner must also be treated.
Urethritis caused by trauma or chemical irritants is treated by avoiding the source of injury or irritation.
Outlook (Prognosis)
With the correct diagnosis and treatment, urethritis usually clears up without any complications. However, urethritis can lead to permanent damage to the urethra (scar tissue called urethral stricture) and other urinary organs in both men and women.
Possible Complications
Men with urethritis are at risk for the following complications:
Call your health care provider if you have symptoms of urethritis.
Prevention
Some causes of urethritis may be avoided with good personal hygiene and by practicing safer sexual behaviors such as monogamy (one sexual partner only) and using condoms.
References
Gerber GS, Brendler CB. Evaluation of the urologic patient: history, physical examination, and urinalysis. In: Wein AJ, ed. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 3.
Lentz GM. Urogynecology: physiology of micturition, diagnosis of voiding dysfunction, and incontinence: surgical and nonsurgical treatment. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM, eds. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007: chap 21.
Eckert LO, Lentz GM. Infections of the lower genital tract: vulva, vagina, cervix, toxic shock syndrome, HIV infections. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM, eds. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007: chap 22.
Review Date:
9/7/2008
Reviewed By:
Linda Vorvick, MD, Seattle Site Coordinator, Lecturer, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and Louis S. Liou, MD, PhD, Assistant Professor of Urology, Department of Surgery, Boston University School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.