Toremifene Citrate (TORE-em-i-feen SIT-rate)

Treats metastatic (spreading) breast cancer in postmenopausal (no longer have menstrual periods) women with certain types of tumors.

Brand Name(s):

Fareston

When This Medicine Should Not Be Used:

How to Use This Medicine:

Tablet

• Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
• Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
• You may take this medicine with or without food.

If a dose is missed:

• If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.

How to Store and Dispose of This Medicine:

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
• Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
• Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are also using a thiazide diuretic ("water pill"), such as hydrochlorothiazide (HCTZ), or if you are also using a blood thinner such as warfarin (Coumadin®).
• Make sure your doctor knows if you are also using phenobarbital (Luminal®, Solfoton®), phenytoin (Dilantin®), carbamazepine (Carbatol®, Tegretol®), ketoconazole (Nizoral®), or erythromycin (E-Mycin®, Eryc®, Ery-Tab®, Ilotycin®, PCE®).

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breast feeding. It is unlikely that a postmenopausal woman may become pregnant. But, you should know that using this medicine while you are pregnant could harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.
• Make sure your doctor knows if you have had a blood clot, or if you have a problem that might make you more likely to get one. Make sure your doctor knows if you have liver problems.
• Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
• Clouding of the eyes.
• Heart failure or heart attack.
• Heart, liver, or circulatory problems.

If you notice these less serious side effects, talk with your doctor:

• Dizziness or headache.
• Dry or painful eyes, trouble seeing, or double vision.
• Feeling unusually tired, weak, or sad.
• Hot flashes and sweating.
• Loss of appetite, or nausea or vomiting.
• Loss of coordination.
• Pain, tenderness, or redness in your joints, bones, muscles, trunk, or back.
• Swelling or bloating.
• Vaginal discharge or bleeding.