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Rho(d) immune globulin (Injection)

Rho(D) Immune Globulin (roe (D) im-MYOON GLOB-yoo-lin)

Given to a pregnant woman whose blood type is Rho(D) negative to keep the baby's blood from interacting with the mother's. Also treats a blood cell disorder called idiopathic thrombocytopenic purpura (ITP).

Brand Name(s):

HyperRHO S/D, Rhogam, Micrhogam Ultra-Filtered, MICRhoGAM Ultra-Filtered Plus, RhoGAM Ultra-Filtered Plus, WinRho SDF, Rhophylac

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive Rho(D) immune globulin if you have had an allergic reaction to immune globulin.

How to Use This Medicine:

Injectable

  • An intravenous (in-tra-VEEN-us) or IV injection is given through a tube put in one of your veins, usually in your arm, wrist, hand, or sometimes in your chest.
  • An intramuscular (in-tra-MUS-kyoo-ler) or IM injection is a shot given in the muscle of your upper arm or thigh.
  • A nurse or other caregiver trained to give injections will give your treatment.

If a dose is missed:

  • It is very important that you receive this medicine on a schedule if you are using the medicine during pregnancy. If you are unable to keep an appointment for your injection, call your doctor or caregiver for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Talk to your doctor before getting flu shots or other vaccines while you are receiving this medicine. Vaccines may not work as well, or they could make you ill while you are using this medicine.

Warnings While Using This Medicine:

  • Before using this medicine, tell your doctor if you have immune system disorders.
  • If you are receiving this medicine to treat ITP, tell your doctor if you are pregnant or breastfeeding.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Black, bloody, or tarry stools
  • Chills, fever
  • Lower back or side pain
  • Nausea, vomiting
  • Pinpoint red spots on the skin
  • Problems urinating or urinating less often
  • Rash or hives
  • Unusual bleeding or bruising
  • Wheezing or trouble breathing, chest tightness

If you notice these less serious side effects, talk with your doctor:

  • Headache
  • Joint pain
  • Pain where the injection is given
  • Tiredness

Last Updated: 7/4/2008

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